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Invitrogen
TXNDC3 Polyclonal Antibody
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TXNDC3 Antibody (PA5-22176) in IHC (P)
TXNDC3 Polyclonal Antibody detects TXNDC3 protein at cytoplasm on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. TXNDC3 Polyclonal Antibody (Product # PA5-22176) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-22176
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human TXNDC3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NM23-H8; NME/NM23 family member 8; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3
基因别名: CILD6; HEL-S-99; NM23-H8; NME8; sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427
Entrez Gene ID: (Human) 51314
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
multicellular organism development
spermatogenesis
cell differentiation
sperm motility
cellular response to reactive oxygen species
cilium assembly
cell redox homeostasis
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
