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Agrisera
TYLCV C1/Tomato yellow leaf curl virus coat protein C1 Polyclonal Antibody
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产品信息
AS15-3055
产品规格
种属反应
Virus
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment of C1 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 25 µL of sterile water.
Specific Species Reactivity: Tomato yellow leaf curl virus coat 40 kDa
靶标信息
TYLCV C1 is a complementary-sense gene encoded by the monopartite circular single-stranded DNA genome of Tomato yellow leaf curl virus (a begomovirus, family Geminiviridae), positioned in the complementary-sense transcription unit adjacent to the intergenic region that contains the bidirectional promoter and origin of replication; its coding sequence also fully embeds the C4 open reading frame in an alternative reading frame. The C1 product (Rep) is a multifunctional replication initiator protein organized into an N-terminal origin-recognition/endonuclease region required for rolling-circle replication (including the conserved catalytic tyrosine used to nick and rejoin viral DNA at the origin), followed by regions supporting oligomerization and a P-loop NTP-binding/helicase-like ATPase module that provides ATP hydrolysis essential for viral DNA replication and associated DNA-unwinding activities. Functionally, Rep is the only viral protein strictly required to initiate and drive replication of the viral genome in host nuclei: it specifically binds the origin sequence in the intergenic region, introduces the initiating nick to launch rolling-circle replication, and couples ATP-dependent activities to support productive amplification of viral DNA, thereby enabling systemic infection and serving as a key determinant recognized by certain tomato resistance proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AL1; Rep; Rep/C1; replication-associated protein; replicator initiator protein
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