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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total TYMP.
A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: endothelial cell growth factor 1 (platelet-derived); Gliostatin; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PD-ECGF; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; Thymidine phosphorylase; TP
基因别名: 2900072D10Rik; ECGF1; PD-ECGF; PDECGF; Pdgfec; TYMP
UniProt ID: (Rat) Q5FVR2, (Mouse) Q99N42
Entrez Gene ID: (Rat) 315219, (Mouse) 72962