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Rockland
Transferrin Polyclonal Antibody
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产品信息
600-401-255
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse Transferrin
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Analysis by SDS-PAGE was used to determine that this preparation is substantially free of aggregates and shows a banding pattern consistent with purified Rabbit IgG.
靶标信息
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-1 metal-binding globulin; DKFZp781D0156; hypotransferrinemia with hemochromatosis; Serotransferrin; Siderophilin; transferin; Transferrin
基因别名: AI266983; Cd176; HP; hpx; Tf; Tfn; Trf
UniProt ID: (Mouse) Q921I1
Entrez Gene ID: (Mouse) 22041
transport
ion transport
iron ion transport
cellular iron ion homeostasis
actin filament organization
activation of JUN kinase activity
ferric iron transport
osteoclast differentiation
positive regulation of myelination
iron ion transmembrane transport
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
iron ion homeostasis
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
positive regulation of cell motility
