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Invitrogen
Transferrin Polyclonal Antibody
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Product Details
PA5-29568
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Transferrin. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.51 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2, rat plasma.
Predicted reactivity: Chimpanzee (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin
Gene Aliases: HEL-S-71p; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf
UniProt ID: (Human) P02787, (Rat) Q64630
Entrez Gene ID: (Human) 7018, (Rat) 24825
retina homeostasis
platelet degranulation
cellular iron ion homeostasis
regulation of protein stability
transferrin transport
positive regulation of receptor-mediated endocytosis
iron ion homeostasis
cellular response to iron ion
ferrous iron import into cell
response to hypoxia
iron ion transport
apoptotic process
acute-phase response
actin filament organization
activation of JUN kinase activity
small GTPase mediated signal transduction
response to lead ion
response to organic cyclic compound
ferric iron transport
osteoclast differentiation
positive regulation of myelination
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
positive regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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