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Proteintech
Transferrin Recombinant Rabbit Monoclonal Antibody (5O7)
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产品信息
81676-1-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5O7
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: EGTCQEAPTD ECKPVKWCAL SHHERLKCDE WSVNSVGKIE CVSAETTEDC IAKIMNGEAD AMSLDGGFVY IAGKCGLVPV LAENYNKSDN CEDTPEAGYF AVAVVKKSAS DLTWDNLKGK KSCHTAVGRT AGWNIPMGLL YNKINHCRFD EFFSEGCAPG SKKDSSLCKL CMGSGLNLCE PNNKEGYYGY TGAFRCLVEK GDVAFVKHQT VPQNTGGKNP DPWAKNLNEK DYELLCLDGT RKPVEEYANC HLARAPNHAV VTRKDKEACV HKILRQQQHL FGSNVTDCSG NFCLFRSETK DLLFRDDTVC LAKLHDRNTY EKYLGEEYVK AVGNLRKCST SSLLEACTFR RP
靶标信息
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; hypotransferrinemia with hemochromatosis; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin
基因别名: AI266983; Cd176; HEL-S-71p; HP; hpx; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf
UniProt ID: (Human) P02787, (Rat) Q64630, (Mouse) Q921I1
Entrez Gene ID: (Human) 7018, (Rat) 24825, (Mouse) 22041
retina homeostasis
platelet degranulation
cellular iron ion homeostasis
regulation of protein stability
transferrin transport
positive regulation of receptor-mediated endocytosis
iron ion homeostasis
cellular response to iron ion
ferrous iron import into cell
response to hypoxia
iron ion transport
apoptotic process
acute-phase response
actin filament organization
activation of JUN kinase activity
small GTPase mediated signal transduction
response to lead ion
response to organic cyclic compound
ferric iron transport
osteoclast differentiation
positive regulation of myelination
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
positive regulation of cell motility
transport
ion transport
iron ion transmembrane transport
