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Invitrogen
TrkA/TrkB/TrkC Recombinant Rabbit Monoclonal Antibody (RM423)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-36218
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM423
抗原
A peptide corresponding to the C-terminus of human TRK
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.08 mg/mL
规格
8 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 1% BSA
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-36218 reacts to human TRK. This antibody may also react to mouse or rat TRK, as predicted by immunogen homology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BDNF-tropomyosine receptor kinase B; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp140trk; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 3; NTRK2; NTRK3; Oncogene TRK; splice variant; TEL-TrkC fusion protein; trk tyrosine-specific protein kinase; TRK1-transforming tyrosine kinase protein; TrkB; TrkB-T-Shc; trkC; tropomyosin receptor kinase A; tropomyosin-related kinase A; tropomyosin-related kinase B; truncated trkB; tyrosine kinase receptor A; tyrosine kinase receptor B; tyrosine kinase receptor C; unnamed protein product
基因别名: DEE58; EIEE58; gp145(trkC); GP145-TrkB; GP145-TrkC; MTC; OBHD; p140-TrkA; TRK; Trk-A; trk-B; TRK1; TRKA; TRKB; TRKC
UniProt ID: (Human) P04629, (Human) Q16620, (Human) Q16288
Entrez Gene ID: (Human) 4914, (Human) 4915, (Human) 4916
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
GPI-linked ephrin receptor activity
neurotrophin receptor activity
neurotrophin p75 receptor binding
protein binding
ATP binding
nerve growth factor receptor activity
kinase binding
identical protein binding
protein homodimerization activity
neurotrophin binding
nerve growth factor binding
protease binding
brain-derived neurotrophic factor binding
brain-derived neurotrophic factor-activated receptor activity
p53 binding
neuron migration
transmembrane receptor protein tyrosine kinase signaling pathway
learning
circadian rhythm
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of neuron projection development
central nervous system neuron development
cerebral cortex development
neuron differentiation
brain-derived neurotrophic factor receptor signaling pathway
neurotrophin signaling pathway
regulation of GTPase activity
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
protein autophosphorylation
oligodendrocyte differentiation
peripheral nervous system neuron development
positive regulation of axonogenesis
regulation of protein kinase B signaling
positive regulation of protein kinase B signaling
long-term synaptic potentiation
trans-synaptic signaling by BDNF, modulating synaptic transmission
negative regulation of beta-amyloid formation
cellular response to brain-derived neurotrophic factor stimulus
negative regulation of anoikis
protein phosphorylation
spermatogenesis
axon guidance
learning or memory
negative regulation of cell proliferation
response to xenobiotic stimulus
programmed cell death involved in cell development
peptidyl-tyrosine phosphorylation
olfactory nerve development
neuron projection development
response to nutrient levels
response to nicotine
peptidyl-tyrosine autophosphorylation
nerve growth factor signaling pathway
negative regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of Ras protein signal transduction
neurotrophin TRK receptor signaling pathway
ephrin receptor signaling pathway
sympathetic nervous system development
neuron development
response to axon injury
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
response to hydrostatic pressure
response to electrical stimulus
positive regulation of synaptic transmission, glutamatergic
Sertoli cell development
axonogenesis involved in innervation
positive regulation of ERK1 and ERK2 cascade
cellular response to nicotine
cellular response to beta-amyloid
cellular response to nerve growth factor stimulus
cell communication
heart development
positive regulation of cell migration
animal organ development
system development
positive regulation of positive chemotaxis
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