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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1) encodes a key E1 enzyme that initiates the ubiquitin-proteasome system, which controls protein degradation and turnover in cells. UBA1 activates ubiquitin in an ATP-dependent manner and transfers it to E2 conjugating enzymes, enabling the tagging of target proteins for degradation or other regulatory processes. It is essential for cell viability and has been implicated in disorders such as X-linked spinal muscular atrophy and VEXAS syndrome when mutated.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A1S9T and BN75 temperature sensitivity complementing; POC20 centriolar protein homolog; testicular secretory protein Li 63; UBA1, ubiquitin-activating enzyme E1 homolog A; unnamed protein product
基因别名: A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; SMAX2; UBA1A; UBE1; UBE1X; VEXAS
UniProt ID: (Human) P22314
Entrez Gene ID: (Human) 7317