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Invitrogen
UBD Polyclonal Antibody
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产品信息
PA5-80201
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Diubiquitin (27-40aa YDSVKKIKEHVRSK).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA Cell, SKOV Cell, MCF-7 Cell, A549 Cell, SMMC Cell. IHC: Human Intestinal Cancer Tissue, Human Tonsil Tissue.
靶标信息
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Diubiquitin; UBD 3; Ubiquitin D; Ubiquitin-like protein FAT10
基因别名: FAT10; GABBR1; UBD; UBD-3
UniProt ID: (Human) O15205
Entrez Gene ID: (Human) 10537
proteolysis
ubiquitin-dependent protein catabolic process
response to organonitrogen compound
protein ubiquitination
protein modification by small protein conjugation
response to interferon-gamma
response to tumor necrosis factor
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
aggresome assembly
