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          • Primary Antibodies ›
          • UBE2D1/2/3/4 Antibodies

          Proteintech

          UBE2D1/2/3/4 Monoclonal Antibody (1C7D12), CoraLite® Plus 488

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          Cite UBE2D1/2/3/4 Monoclonal Antibody (1C7D12), CoraLite® Plus 488

          Additional Information:
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          • 抗体检测数据 (1)
          UBE2D1/2/3/4 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          UBE2D1/2/3/4 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 1

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          UBE2D1/2/3/4 Antibody (CL488-68138) in ICC/IF

          Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using CoraLite® Plus 488 UBE2D1/2/3/4 antibody (CL488-68138, Clone: 1C7D12) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          UBE2D1/2/3/4 Antibody in Immunocytochemistry (ICC/IF)
          UBE2D1/2/3/4 Monoclonal Antibody (1C7D12), CoraLite® Plus 488

          产品信息

          CL488-68138

          应用
          建议稀释比
          已发表文章

          免疫细胞化学 (ICC/IF)

          1:50-1:500
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          1C7D12

          抗原

          UBE2D1/2/3/4 fusion protein Ag2278
          查看免疫原

          偶联物

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • Request custom conjugation

          激发/发射光谱

          493/522 nm

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein G

          保存液

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          内含物

          0.05% ProClin 300

          保存条件

          -20°C, store in dark

          运输条件

          Wet ice

          产品详细信息

          Immunogen sequence: MALKRINKE LSDLARDPPA QCSAGPVGDD MFHWQATIMG PNDSPYQGGV FFLTIHFPTD YPFKPPKVAF TTRIYHPNIN SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT DRDKYNRISR EWTQKYAM

          靶标信息

          Ubiquitination is a post-translational modification pathway or is part of the specific protein-degradation pathway by the 26S proteasome. Ubiquitination of a target protein involves multistep enzymatic reaction catalyzed by a cascade of enzymes including Ub-activating enzymes (E1s), Ub-conjugating enzymes (E2s) and Ub ligases (E3s) (PMID: 23542885). UBE2D family, which has 4 members named as UBE2D1/2/3/4, is an E2 ubiquitin-conjugating enzyme family in the ubiquitin-proteasome system. This antibody can recognize all the four members of UBE2D due to the high homology.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: (E3-independent) E2 ubiquitin-conjugating enzyme D1; (E3-independent) E2 ubiquitin-conjugating enzyme D2; (E3-independent) E2 ubiquitin-conjugating enzyme D3; E2 ubiquitin-conjugating enzyme D1; E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2B; E2 ubiquitin-conjugating enzyme D3; E2 ubiquitin-conjugating enzyme D4; E2(17)KB 1; E2(17)KB 2; E2(17)KB 2B; E2(17)KB 3; HBUCE1; p53-regulated ubiquitin-conjugating enzyme 1; PAPase; Phosphoarginine phosphatase; predicted protein of HQ2116; SFT; similar to UBC4/5 in yeast; Stimulator of Fe transport; ubc2e ubiquitin conjugating enzyme; UBC4/5 homolog; UbcH5; UBE2D1/UBE2D3/UBE2D3/UBE2D4; UBE2D3; Ubiquitin carrier protein D1; Ubiquitin carrier protein D2; Ubiquitin carrier protein D2B; Ubiquitin carrier protein D3; Ubiquitin carrier protein D4; ubiquitin conjugating enzyme E2 D4 (putative); ubiquitin conjugating enzyme E2D 1; ubiquitin conjugating enzyme E2D 2; ubiquitin conjugating enzyme E2D 3; ubiquitin conjugating enzyme E2D 4 (putative); Ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2 D2B; Ubiquitin-conjugating enzyme E2 D3; Ubiquitin-conjugating enzyme E2 D4; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2(17)KB 2B; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-conjugating enzyme E2-17 kDa 2B; Ubiquitin-conjugating enzyme E2-17 kDa 3; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme HBUCE1; Ubiquitin-protein ligase D1; Ubiquitin-protein ligase D2; Ubiquitin-protein ligase D2B; Ubiquitin-protein ligase D3; Ubiquitin-protein ligase D4; unnamed protein product

          查看更多 收起

          基因别名: 1100001F19Rik; 9430029A22Rik; AA414951; E2(17)KB1; E2(17)KB2; E2(17)KB3; E217kB; HBUCE1; PUBC1; RGD69425; SFT; Ubc2e; UBC4; UBC4/5; UBC5A; UBC5B; UBC5C; UBCH4; UBCH5; UBCH5A; UBCH5B; UBCH5C; UBCH5D; UBE2D1; UBE2D2; Ube2d2b; UBE2D3; UBE2D4

          查看更多 收起

          UniProt ID: (Human) P51668, (Human) P62837, (Human) P61077, (Human) Q9Y2X8, (Mouse) P61080, (Rat) D3ZDK2, (Rat) P62839, (Mouse) P61079, (Rat) P61078, (Rat) P70711

          查看更多 收起

          Entrez Gene ID: (Human) 7321, (Human) 7322, (Human) 7323, (Human) 51619, (Mouse) 216080, (Rat) 361831, (Rat) 641452, (Mouse) 66105, (Rat) 81920, (Rat) 79435

          查看更多 收起

          功能
          nucleotide binding ubiquitin-protein transferase activity protein binding ATP binding transferase activity ubiquitin protein ligase activity ubiquitin conjugating enzyme activity ligase activity molecular_function ubiquitin-protein ligase
          参与通路
          negative regulation of transcription from RNA polymerase II promoter protein polyubiquitination ubiquitin-dependent protein catabolic process protein ubiquitination negative regulation of BMP signaling pathway positive regulation of protein ubiquitination cellular response to nutrient levels TORC1 signaling proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination positive regulation of protein polyubiquitination negative regulation of TORC1 signaling protein modification process protein autoubiquitination DNA repair protein monoubiquitination apoptotic process cellular response to DNA damage stimulus protein K11-linked ubiquitination protein K6-linked ubiquitination positive regulation of protein targeting to mitochondrion protein K29-linked ubiquitination protein K27-linked ubiquitination protein K63-linked ubiquitination metabolic process biological_process
          It has to be done as per old AB suggested Products section.

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