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Invitrogen
UBE2T Polyclonal Antibody
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UBE2T Antibody (PA5-72394) in WB
Western blot analysis of UBE2T in HeLa cell lysate using 35 µg of protein per lane. Samples were probed with UBE2T polyclonal antibody (Product # PA5-72394) with a dilution of 1:1000, and a goat anti-rabbit IgG H&L (HRP) secondary antibody with a dilution of 1:5000.
产品信息
PA5-72394
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
region 140-169 aa
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
靶标信息
UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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