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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: VTTSSEMQQC IQMEQKRWIQ LFKVITNLVK MLKSRDTRRN FCPPNHWLSE QEDIKADKVT QLYVPASRHV WRFRRMGRIG PLQSTLDVGL ESPPLSVSE
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HECT-type ubiquitin transferase E3C; homologous to E6AP carboxyl terminus homologous protein 2; KIAA0010; RTA-associated ubiquitin ligase; ubiquitin-protein isopeptide ligase (E3); unnamed protein product
基因别名: HECTH2; NDSMBA; NEDSMBA; RAUL
UniProt ID: (Human) Q15386
Entrez Gene ID: (Human) 9690