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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: LAERIKSLAD LQQQEEETYA DACDEFLDPI MSTLMCDPVV LPSSRVTVDR STIARHLLSD QTDPFNRSPL TMDQIRPNTE LKEKIQRWLA ERKQQKEQLE
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KIAA0126; liver regeneration-related protein LRRG073; RING-type E3 ubiquitin transferase E4 A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; unnamed protein product
基因别名: 4732444G18Rik; 9930123J21Rik; Ab2-232; E4; NEDHMS; UBOX2; UFD2; UFD2b
UniProt ID: (Human) Q14139, (Rat) Q6P7A2, (Mouse) E9Q735
Entrez Gene ID: (Human) 9354, (Rat) 315608, (Mouse) 140630