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Invitrogen
UBP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-110678
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TAYVNNSPSP APTFTSPQQS TCSVPDSNSS SPNHQGDGAS QTSGEQIQPS ATIQETQQWL LKNRFSSYTR LFSNFSGADL LKLTKEDLVQ ICGAADGIRL YNSLKSRSVR PRLTIYVCRE QPSSTVLQGQ QQAASSASEN GSGA
Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 90%.
靶标信息
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: transcription factor CP2 like 5; transcription factor LBP-1; unnamed protein product
基因别名: LBP-1a; LBP-1B; LBP1A; LBP1B; TFCP2L5
UniProt ID: (Human) Q9NZI7
Entrez Gene ID: (Human) 7342
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
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