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Invitrogen
UGCG Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-54986
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RLHLNKKATD KQPYSKLPGV SLLKPLKGVD PNLINNLETF FELDYPKYEV LLCVQDHDDP AIDVCKKLLG KYPNVDARLF IGGKKVGINP KINNLMPGYE VAKYDLI
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
靶标信息
May serve as a "flippase" as well as a glucosyltransferase that transfers glucose to ceramide. It Catalyzes; UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glucosylceramide synthase; glycosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; unnamed protein product
基因别名: GCS; GLCT1
UniProt ID: (Human) Q16739
Entrez Gene ID: (Human) 7357
protein lipidation
sphingolipid metabolic process
glucosylceramide biosynthetic process
glycosphingolipid biosynthetic process
epidermis development
regulation of signal transduction
cell differentiation
keratinocyte differentiation
leptin-mediated signaling pathway
neuron development
establishment of skin barrier
intestinal lipid absorption
cornified envelope assembly
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
