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Invitrogen
UGT1A10 Polyclonal Antibody
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UGT1A10 Antibody (PA5-51151) in WB
Western Blot analysis of UGT1A10 was performed using Lane 1-3: 231, HeLa, and mouse liver tissue cells. The membrane was probed with UGT1A10 Polyclonal Antibody (Product # PA5-51151) 1:300 dilution. Secondary antibody: Goat anti rabbit IgG at 1:8,000 dilution. Exposure time: 10 seconds.
产品信息
PA5-51151
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein of human UGT1A10
偶联物
形式
Liquid
浓度
3.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total UGT1A10 protein.
靶标信息
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: UDP glucuronosyltransferase 1 family, polypeptide A10; UDP glycosyltransferase 1 family polypeptide A13; UDP glycosyltransferase 1 family, polypeptide A10; UDP-glucuronosyltransferase 1-10; UDP-glucuronosyltransferase 1-7C; UDP-glucuronosyltransferase 1-J; UDP-glucuronosyltransferase 1A10; UDP-glucuronosyltransferase 1A7; UDP-glucuronosyltransferase 1A7C; UDPGT 1-10; UDPGT 1-7C; UGT-1J; UGT1*7C; UGT1-07C; UGT1.7C; UGT1A10; UGT1A7
基因别名: A10'; A13; GNT1; UDPGT; UGT-1J; UGT1; UGT1-10; UGT1.10; UGT1A10; Ugt1a13; Ugt1a7; Ugt1a7c; UGT1J
UniProt ID: (Human) Q7Z6H8, (Mouse) Q6ZQM8
Entrez Gene ID: (Human) 54575, (Mouse) 394430, (Mouse) 394432
retinoic acid binding
protein kinase C binding
glucuronosyltransferase activity
protein homodimerization activity
protein heterodimerization activity
enzyme inhibitor activity
steroid binding
fatty acid binding
drug binding
enzyme binding
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
glycosyltransferase
flavonoid biosynthetic process
flavone metabolic process
cellular glucuronidation
flavonoid glucuronidation
xenobiotic glucuronidation
cellular response to hormone stimulus
negative regulation of catalytic activity
estrogen catabolic process
metabolic process
aromatic compound catabolic process
coumarin catabolic process
