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Proteintech
UHMK1 Polyclonal Antibody
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产品信息
11624-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UHMK1 Fusion Protein Ag2204 (3-344 aa encoded by BC026046)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GSGCAWGAE PPRFLEAFGR LWQVQSRLGS GSSASVYRVR CCGNPGSPPG ALKQFLPPGT TGAAASAAEY GFRKERAALE QLQGHRNIVT LYGVFTIHFS PNVPSRCLLL ELLDVSVSEL LLYSSHQGCS MWMIQHCARD VLEALAFLHH EGYVHADLKP RNILWSAENE CFKLIDFGLS FKEGNQDVKY IQTDGYRAPE AELQNCLAQA GLQSDTECTS AVDLWSLGII LLEMFSGMKL KHTVRSQEWK ANSSATIDHI FASKAVVNAA IPAYHLRDLI KSMLHDDPSR RIPAEMALCS PFFSIPFAPH IEDLVMLPTP VLRLLNVLDD DYLENEEEYE GLC (3-344 aa encoded by BC026046)
靶标信息
Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: kinase interacting stathmin; kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS protein kinase; P-CIP2; PAM COOH-terminal interactor protein 2; Serine/threonine-protein kinase Kist; U2AF homology motif kinase 1
基因别名: 4732477C12Rik; 4930500M09Rik; AA673513; AI449218; AU021979; KIS; KIST; P-CIP2; UHMK1
UniProt ID: (Human) Q8TAS1, (Mouse) P97343, (Rat) Q63285
Entrez Gene ID: (Human) 127933, (Mouse) 16589, (Rat) 246332
mRNA binding
protein serine/threonine kinase activity
protein binding
ATP binding
transferase activity
ribonucleoprotein complex binding
nucleotide binding
nucleic acid binding
RNA binding
protein kinase activity
kinase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
cell cycle arrest
peptidyl-serine phosphorylation
neuron projection development
positive regulation of translational initiation
protein autophosphorylation
regulation of protein export from nucleus
protein phosphorylation
phosphorylation
