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Invitrogen
ULK2 Monoclonal Antibody (218CT21.2.6)
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产品信息
MA5-37498
产品规格
宿主/亚型
Mouse
/ IgM, kappa
分类
Monoclonal
类型
Antibody
克隆号
218CT21.2.6
抗原
ULK2 recombinant protein
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
靶标信息
ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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