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Proteintech
UPB1 Polyclonal Antibody
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产品信息
24603-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UPB1 Fusion Protein Ag18960 (1-384 aa encoded by BC131703)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAGAEWKSL EECLEKHLPL PDLQEVKRVL YGKELRKLDL PREAFEAASR EDFELQGYAF EAAEEQLRRP RIVHVGLVQN RIPLPANAPV AEQVSALHRR IKAIVEVAAM CGVNIICFQE AWTMPFAFCT REKLPWTEFA ESAEDGPTTR FCQKLAKNHD MVVVSPILER DSEHGDVLWN TAVVISNSGA VLGKTRKNHI PRVGDFNEST YYMEGNLGHP VFQTQFGRIA VNICYGRHHP LNWLMYSING AEIIFNPSAT IGALSESLWP IEARNAAIAN HCFTCAINRV GTEHFPNEFT SGDGKKAHQD FGYFYGSSYV AAPDSSRTPG LSRSRDGLLV AKLDLNLCQQ VNDVWNFKMT GRYEMYAREL AEAVKSNYSP TIVKE (1-384 aa encoded by BC131703)
靶标信息
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-alanine synthase; Beta-ureidopropionase; BUP-1; N-carbamoyl-beta-alanine amidohydrolase; ureidopropionase, beta
基因别名: AI195023; BUP1; UPB1
UniProt ID: (Human) Q9UBR1, (Mouse) Q8VC97
Entrez Gene ID: (Human) 51733, (Mouse) 103149
