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Invitrogen
USP22 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-83751
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MVSRPEPEGE AMDAELAVAP PGCSHLGSFK VDNWKQNLRA IYQCF
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 96%.
靶标信息
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deubiquitinating enzyme 22; ubiquitin specific protease 22; ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22
基因别名: USP3L
UniProt ID: (Human) Q9UPT9
Entrez Gene ID: (Human) 23326
G2/M transition of mitotic cell cycle
regulation of DNA repair
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
embryo development ending in birth or egg hatching
protein deubiquitination
positive regulation of type I interferon production
regulation of RNA splicing
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
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