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Invitrogen
UTY Polyclonal Antibody
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UTY Antibody (PA5-117140) in WB
Western blot analysis of UTY in extracts of various cell lines. Samples were incubated with UTY Polyclonal antibody (Product # PA5-117140) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-117140
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_0090563)
偶联物
形式
Liquid
浓度
3.01 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse kidney, Mouse testis, Mouse liver, Rat kidney
Immunogen sequence: MKSCAVSLTT AAVAFGDEAK KMAEGKASRE SEEESVSLTV EEREALGGMD SRLFGFVRLH EDGARTKTLL
靶标信息
UTY encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: histone demethylase UTY; lysine (K)-specific demethylase 6A; lysine-specific demethylase 6A; male-specific histocompatibility antigen H-YDB; ubiquitously transcribed tetratricopeptide repeat gene, X chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome; ubiquitously transcribed tetratricopeptide repeat, X chromosome; ubiquitously transcribed TPR protein on the Y chromosome; ubiquitously transcribed Y chromosome tetratricopeptide repeat protein
基因别名: Hydb; mKIAA4057; RGD1565481; Utx; Uty
Entrez Gene ID: (Rat) 100310845, (Mouse) 22290
RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
identical protein binding
metal ion binding
histone demethylase activity (H3-K27 specific)
sulfonate dioxygenase activity
protein binding
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
dioxygenase activity
histone demethylase activity (H3-K36 specific)
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
chromatin/chromatin-binding, or -regulatory protein
in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
heart development
biological_process
regulation of gene expression
neural tube development
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
embryonic organ development
notochord morphogenesis
canonical Wnt signaling pathway
histone H3-K27 demethylation
cardiovascular system development
chromatin modification
regulation of chromatin silencing
establishment of protein localization
oxidation-reduction process
histone H3-K36 demethylation
cardiac muscle cell contraction
