Proteintech

Uromodulin Polyclonal Antibody

Name: Uromodulin Polyclonal Antibody
Brand: Proteintech
SKU: 32657-1-AP

查看其他14个Uromodulin抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Uromodulin Antibody in Western Blot (WB)

图: 1 / 1

Uromodulin Antibody (32657-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 32660-1-AP (SLAM/CD150 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

Product Image Gallery

Immunogen image

Immunogen Image Uromodulin Polyclonal Antibody

产品信息

32657-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:8,000

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

450 µg/mL

67.5 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Sequence of this protein is as follows: NSTEARRCSE CHNNATCTVD GVVTTCSCQT GFTGDGLVCE DMDECATPWT HNCSNSSCVN TPGSFKCSCQ DGFRLTPELS CTDVDECSEQ GLSNCHALAT CVNTEGDYLC VCPEGFTGDG WYCECSPGSC EPGLDCLPQG PDGKLVCQDP CNTYETLTEY WRSTEYGVGY SCDAGLHGWY RFTGQGGVRM AETCVPVLRC NTAAPMWLNG SHPSSSEGIV SRTACAHWSD QCCRWSTEIQ VKACPGGFYI YNLTAPPECN LAYCTDPSSV EGTCEECRVD EDCISDNGRW RCQCKQDSNI TDVSQLEYRL ECGANDIKMS LRKCQLQSLG FMNVFMYLND RQCSGFSESD ERDWMSIVTP ARNGPCGTVL RRNETHATYS NTLYLANAII IRDIIIRMNF ECSYPLDMKV SLKTSLQPMV SALNISLGGT GKFTVRMALF QSPTYTQPHQ GPSVMLSTEA FLYVGTMLDG GDLSRFVLLM TNCYATPSSN STDPVKYFII QDSCPRTEDT TIQVTENGES SQARFSVQMF RFAGNYDLVY LHCEVYLCDS TSEQCKPTCS GTRFRSGNFI DQTRVLNLGP ITRQGVQASV SKAA

靶标信息

This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

仅用于科研。不用于诊断过程。未经明确授权不得转售。