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Abnova
VDAC1 Monoclonal Antibody (2A8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007416-M28
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A8
抗原
VDAC1 (AAH08482.1, 64 a.a. approximately 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.9 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: WTEYGLTFTE KWNTDNTLGT EITVEDQLAR GLKLTFDSSF SPNTGKKNAK IKTGYKREHI NLGCDMDFDI AGPSIRGALV LG
靶标信息
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1; ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2; ATVDAC1; ATVDAC2; F2G14.210; HSR2; hVDAC1; K9I9.6; K9I9_6; MGC111064; Mitochondrial Porin; outer mitochondrial membrane protein porin 1; plasmalemmal porin; porin 31HL; porin 31HM; PORIN-31-HL; sperm binding protein 1a; T22N4.9; T22N4_9; unnamed protein product; VD; VDAC1; VDAC2
基因别名: PORIN; VDAC-1
UniProt ID: (Human) P21796
Entrez Gene ID: (Human) 7416
anion transport
apoptotic process
epithelial cell differentiation
calcium ion transmembrane import into mitochondrion
pyruvate biosynthetic process
negative regulation of apoptotic process
transmembrane transport
anion transmembrane transport
negative regulation of calcium import into the mitochondrion
regulation of mitophagy
positive regulation of mitophagy
regulation of mitophagy
positive regulation of type 2 mitophagy
mitochondrial transmembrane transport
negative regulation of reactive oxygen species metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
