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Invitrogen
VMP1 Polyclonal Antibody
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VMP1 Antibody (PA5-66716) in WB
Western blot was performed using Anti-VMP1 Polyclonal Antibody (Product # PA5-66716) and a 41 kDa band corresponding to Vacuole membrane protein 1 was observed across all the cell lines tested. Whole cell extracts (30 µg lysate) of PANC-1 (Lane 1), MCF7 (Lane 2) and HeLa (Lane 3) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was probed with the primar... View More
产品信息
PA5-66716
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human VMP1
偶联物
形式
Liquid
浓度
0.6 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: MAENGKNCDQR RVAMNKEHHN GNFTDPSSVN EKKRREREER QNIVLWRQP
Highest antigen sequence identity to the following orthologs - mouse 84%, rat 88%.
靶标信息
VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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