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Proteintech
VPS72 Polyclonal Antibody
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产品信息
15143-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
VPS72 Fusion Protein Ag7424 (1-364 aa encoded by BC003151)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSLAGGRAP RKTAGNRLSG LLEAEEEDEF YQTTYGGFTE ESGDDEYQGD QSDTEDEVDS DFDIDEGDEP SSDGEAEEPR RKRRVVTKAY KEPLKSLRPR KVNTPAGSSQ KAREEKALLP LELQDDGSDS RKSMRQSTAE HTRQTFLRVQ ERQGQSRRRK GPHCERPLTQ EELLREAKIT EELNLRSLET YERLEADKKK QVHKKRKCPG PIITYHSVTV PLVGEPGPKE ENVDIEGLDP APSVSALTPH AGTGPVNPPA RCSRTFITFS DDATFEEWFP QGRPPKVPVR EVCPVTHRPA LYRDPVTDIP YATARAFKII REAYKKYITA HGLPPTASAL GPGPPPPEPL PGSGPRALRQ KIVIK (1-364 aa encoded by BC003151)
靶标信息
Vacuolar protein sorting-associated protein 72 homolog (VPS72), also known as VPS72 or Transcription factor-like 1, is a 364 amino acid subunit of the TRRAP/TIP60 HAT complex. VPS72 has also been identified as a subunit of a novel complex containing SNF2-related helicase SRCAP (SWI2/SNF2-related CBP activator protein). This SRCAP-containing complex is very similar to the S. cerevisiae SWR1 chromatin remodeling complex. The involvement of VPS72 in these complexes has suggested that VPS72 plays multiple roles in chromatin modification and remodeling in cells. VPS72 localizes to the nucleus and is phosphorylated upon DNA damage, most likely by ATM or ATR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein YL-1; T YL-1; Transcription factor-like 1; transformation suppressor gene YL-1; Vacuolar protein sorting-associated protein 72 homolog
基因别名: CFL1; Swc2; TCFL1; VPS72; YL-1; YL1
UniProt ID: (Human) Q15906, (Mouse) Q62481
Entrez Gene ID: (Human) 6944, (Rat) 310661, (Mouse) 21427
