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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 90%, Rat- 43%.
Sequence of this protein is as follows: SLSGKVSLPC HFSTMPTLPP SYNTSEFLRI KWSKIEVDKN GKDLKETTVL VAQNGNIKIG QDYKGRVSVP THPEAVGDAS LTVVKLLASD AGLYRCDVMY GIEDTQDTVS LTVDGVVFHY RAATSRYTLN FEAA
Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican's existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chondroitin sulfate proteoglycan 2; Chondroitin sulfate proteoglycan core protein 2; GHAP; Glial hyaluronate-binding protein; Large fibroblast proteoglycan; PG-M; PGM; V1 Neo; Versican core protein; Versican V0; WGN 1
基因别名: CSPG2; VCAN
Entrez Gene ID: (Human) 1462