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Proteintech
Villin Monoclonal Antibody (2B7B9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
66096-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2B7B9
抗原
Villin Fusion Protein Ag9637 (1-350 aa encoded by BC017303)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.89 mg/mL
规格
133.5 µg
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTKLSAQVK GSLNITTPGL QIWRIEAMQM VPVPSSTFGS FFDGDCYIIL AIHKTASSLS YDIHYWIGQD SSLDEQGAAA IYTTQMDDFL KGRAVQHREV QGNESEAFRG YFKQGLVIRK GGVASGMKHV ETNSYDVQRL LHVKGKRNVV AGEVEMSWKS FNRGDVFLLD LGKLIIQWNG PESTRMERLR GMTLAKEIRD QERGGRTYVG VVDGENELAS PKLMEVMNHV LGKRRELKAA VPDTVVEPAL KAALKLYHVS DSEGNLVVRE VATRPLTQDL LSHEDCYILD QGGLKIYVWK GKKANEQEKK GAMSHALNFI KAKQYPPSTQ VEVQNDGAES AVFQQLFQKW T (1-350 aa encoded by BC017303)
靶标信息
Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: OTTHUMP00000207159; unnamed protein product
基因别名: D2S1471; VIL
UniProt ID: (Human) P09327, (Mouse) Q62468
Entrez Gene ID: (Human) 7429, (Mouse) 22349
intestinal D-glucose absorption
cytoskeleton organization
actin filament organization
epidermal growth factor receptor signaling pathway
actin polymerization or depolymerization
regulation of cell shape
response to bacterium
positive regulation of epithelial cell migration
actin filament polymerization
actin filament depolymerization
positive regulation of cell migration
positive regulation of actin filament depolymerization
epithelial cell differentiation
positive regulation of actin filament bundle assembly
regulation of microvillus length
cellular response to hepatocyte growth factor stimulus
positive regulation of multicellular organism growth
positive regulation of cellular component biogenesis
actin filament severing
barbed-end actin filament capping
regulation of actin nucleation
actin filament capping
cytoplasmic actin-based contraction involved in cell motility
regulation of wound healing
protein-containing complex assembly
cellular response to epidermal growth factor stimulus
positive regulation of lamellipodium organization
terminal web assembly
positive regulation of protein localization to plasma membrane
regulation of lamellipodium morphogenesis
positive regulation of lamellipodium morphogenesis
microvillus assembly
regulation of plasma membrane bounded cell projection organization
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