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Invitrogen
WBP1L Monoclonal Antibody (OPAL1-01)
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WBP1L Antibody (MA5-28627) in WB
Western blotting analysis of human OPAL1 using mouse Monoclonal antibody OPAL1-01 (Product # MA5-28627) on lysates of HEK-293T/OPAL1 transfectants, and of murine splenocytes and HEK-293T cells (negative controls) under reducing and non-reducing conditions. Nitrocellulose membrane was probed with 2µg/mL of mouse anti-OPAL1 monoclonal antibody followed by IRDye800-conjugated anti-mouse secondary antibody. OPAL1 was detected at around 45-60kDa.
产品信息
MA5-28627
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OPAL1-01
抗原
Recombinant fragment of human OPAL1 (amino acids 152-342)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 8
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megakaryocytes and platelets.
Western Blot: non-reducing conditions recommended.
靶标信息
WBP1L (OPAL1, outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megakaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Outcome predictor in acute leukemia 1; WW domain binding protein 1-like
基因别名: C10orf26; OPA1L; OPAL1; WBP1L
UniProt ID: (Human) Q1EG70
Entrez Gene ID: (Human) 54838
