Proteintech

WDR5 Polyclonal Antibody

Name: WDR5 Polyclonal Antibody
Brand: Proteintech
SKU: 15544-1-AP

3 篇参考文献

查看其他26个WDR5抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (13)

WDR5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 13

WDR5 Antibody (15544-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using (Product # 15544-1-AP) (WDR5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Product Image Gallery

Immunogen image

Immunogen Image WDR5 Polyclonal Antibody

产品信息

15544-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

染色质免疫沉淀实验 (ChIP)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

WDR5 Fusion Protein Ag7900 (1-334 aa encoded by BC001635)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.13 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

The WDR5 antibody targets the WD repeat protein domain 5 (WDR5), a member of the WD40 repeat protein family in humans.

Immunogen sequence: MATEEKKPE TEAARAQPTP SSSATQSKPT PVKPNYALKF TLAGHTKAVS SVKFSPNGEW LASSSADKLI KIWGAYDGKF EKTISGHKLG ISDVAWSSDS NLLVSASDDK TLKIWDVSSG KCLKTLKGHS NYVFCCNFNP QSNLIVSGSF DESVRIWDVK TGKCLKTLPA HSDPVSAVHF NRDGSLIVSS SYDGLCRIWD TASGQCLKTL IDDDNPPVSF VKFSPNGKYI LAATLDNTLK LWDYSKGKCL KTYTGHKNEK YCIFANFSVT GGKWIVSGSE DNLVYIWNLQ TKEIVQKLQG HTDVVISTAC HPTENIIASA ALENDKTIKL WKSDC (1-334 aa encoded by BC001635)

靶标信息

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: BMP2-induced 3-kb gene protein; cilia and flagella associated protein 89; SWD3, Set1c WD40 repeat protein, homolog; WD repeat-containing protein 5; WD repeat-containing protein BIG-3

查看更多收起

基因别名: 2410008O07Rik; AA408785; AA960360; Big; BIG-3; BIG3; CFAP89; SWD3; WDR5

查看更多收起

UniProt ID: (Human) P61964, (Mouse) P61965, (Rat) Q498M4

查看更多收起

Entrez Gene ID: (Human) 11091, (Mouse) 140858, (Rat) 362093

查看更多收起

功能

protein binding histone-lysine N-methyltransferase activity methylated histone binding histone methyltransferase activity (H3-K4 specific) histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K16 specific)

参与通路