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Invitrogen
WFS1 Polyclonal Antibody
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产品信息
PA1-16923
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 110 amino acid region of the N-terminal region of the human WFS1 protein.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
In Western blot, bands are observed at ~100 kDa and ~200 kDa representing the monomer and dimer forms of WFS1.
Suggested positive control: antigen standard for WFS1 (transient overexpression lysate).
靶标信息
WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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