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Invitrogen
WHSC2 Polyclonal Antibody
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产品信息
PA1-25706
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Amino acids 334-525 of WHSC2
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-25706 detects WHSC2 from human, mouse, and rat samples.
PA1-25706 has been successfully used in Western blot procedures.
The PA1-25706 immunogen corresponds to amino acids 334-525 of WHSC2.
PA1-25706 has a predicted molecular weight of 61 kDa.
靶标信息
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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