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WIPI1 Monoclonal Antibody (3C1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055062-M02
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C1
抗原
WIPI1 (NP_060453.2, 348 a.a. approximately 445 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: GGECVLIKTH SLLGSGTTEE NKENDLRPSL PQSYAATVAR PSASSASTVP GYSEDGGALR GEVIPEHEFA TGPVCLDDEN EFPPIILCRG NQKGKTKQ
靶标信息
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: atg18 protein homolog; unnamed protein product; WIPI-1 alpha; WIPI49; WD-repeat protein; 7-bladed beta propeller
基因别名: ATG18; ATG18A; RGD1307754; WIPI49
UniProt ID: (Human) Q5MNZ9
Entrez Gene ID: (Human) 55062, (Rat) 303630
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