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Invitrogen
WRCH1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-62018
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LREDVKVLIE LDKCKEKPVP EEAA
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2310026M05Rik; CDC42-like GTPase 1; GTP-binding protein like 1; GTP-binding protein SB128; ras homolog gene family, member U; ras-like gene family member U; Rho family GTPase; rho GTPase-like protein ARHU; Ryu GTPase; unnamed protein product; wnt-1 responsive Cdc42 homolog 1
基因别名: ARHU; CDC42L1; G28K; hG28K; WRCH1
UniProt ID: (Human) Q7L0Q8
Entrez Gene ID: (Human) 58480
endocytosis
cytoskeleton organization
actin filament organization
signal transduction
small GTPase mediated signal transduction
regulation of cell shape
establishment of cell polarity
regulation of small GTPase mediated signal transduction
positive regulation of focal adhesion disassembly
positive regulation of establishment of protein localization to mitochondrion
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