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Proteintech
Willin Polyclonal Antibody
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产品信息
21039-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Willin Fusion Protein Ag15375 (359-622 aa encoded by BC029870)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors. This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
Immunogen sequence: LDMDQLEKR SRASGSSAGS MKHKRLSRHS TASHSSSHTS GIEADTKPRD TGPEDSYSSS AIHRKLKTCS SMTSHGSSHT SGVESGGKDR LEEDLQDDEI EMLVDDPRDL EQMNEESLEV SPDMCIYITE DMLMSRKLNG HSGLIVKEIG SSTSSSSETV VKLRGQSTDS LPQTICRKPK TSTDRHSLSL DDIRLYQKDF LRIAGLCQDT AQSYTFGCGH ELDEEGLYCN SCLAQQCINI QDAFPVKRTS KYFSLDLTHD EVPEFVV (359-622 aa encoded by BC029870 )
靶标信息
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4.1 ezrin radixin moesin (FERM)-containing protein; expanded homolog; FERM domain-containing protein 163SCII; FERM domain-containing protein 6; FERM-domain-containing protein 163SCII; MGC17921; Willin
基因别名: 2610019M19Rik; 4930488L10Rik; AW212977; c14_5320; C14orf31; EX1; FRMD6; Willin
UniProt ID: (Human) Q96NE9, (Mouse) Q8C0V9
Entrez Gene ID: (Human) 122786, (Rat) 257646, (Mouse) 319710
