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Proteintech
XRCC1 Polyclonal Antibody
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产品信息
21468-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
XRCC1 Fusion Protein Ag15172 (284-633 aa encoded by BC023593)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TAPVPARAQ GAVTGKPRGE GTEPRRPRAG PEELGKILQG VVVVLSGFQN PFRSELRDKA LELGAKYRPD WTRDSTHLIC AFANTPKYSQ VLGLGGRIVR KEWVLDCHRM RRRLPSQRYL MAGPGSSSEE DEASHSGGSG DEAPKLPQKQ PQTKTKPTQA AGPSSPQKPP TPEETKAASP VLQEDIDIEG VQSEGQDNGA EDSGDTEDEL RRVAEQKEHR LPPGQEENGE DPYAGSTDEN TDSEEHQEPP DLPVPELPDF FQGKHFFLYG EFPGDERRKL IRYVTAFNGE LEDYMSDRVQ FVITAQEWDP SFEEALMDNP SLAFVRPRWI YSCNEKQKLL PHQLYGVVPQ A (284-633 aa encoded by BC023593)
靶标信息
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1
基因别名: RCC; Xrcc-1; XRCC1
UniProt ID: (Human) P18887, (Mouse) Q60596
Entrez Gene ID: (Human) 7515, (Mouse) 22594
single strand break repair
double-strand break repair via homologous recombination
response to hypoxia
transcription-coupled nucleotide-excision repair
base-excision repair
base-excision repair, DNA ligation
nucleotide-excision repair, DNA gap filling
response to organic substance
response to drug
DNA repair
cellular response to DNA damage stimulus
hippocampus development
