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Invitrogen
XRCC2 Polyclonal Antibody
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产品信息
PA5-32643
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide from the N-terminus of human XRCC2
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.6, with 1% BSA
内含物
<0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is testis tissue.
靶标信息
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp781P0919; DNA repair protein XRCC2; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross-complementing protein 2
基因别名: FANCU; XRCC2
UniProt ID: (Human) O43543
Entrez Gene ID: (Human) 7516
mitotic cell cycle
meiotic DNA recombinase assembly
double-strand break repair via homologous recombination
DNA synthesis involved in DNA repair
strand displacement
in utero embryonic development
somitogenesis
DNA repair
mitotic recombination
meiotic nuclear division
reciprocal meiotic recombination
response to X-ray
response to ionizing radiation
response to gamma radiation
multicellular organism growth
strand invasion
negative regulation of neuron apoptotic process
positive regulation of neurogenesis
centrosome organization
regulation of fibroblast apoptotic process
