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Invitrogen
XRCC3 Polyclonal Antibody
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XRCC3 Antibody (PA5-96066) in WB
Western blot analysis of XRCC3 in extracts of HL-60 cells. Samples were incubated with XRCC3 Polyclonal antibody (Product # PA5-96066) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96066
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3 (NP_0010935881)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.84 mg/mL
规格
84 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ILTALQLHQQ KERFPTQHQR LSLGCPVLDA LLRGGLPLDG ITELAGRSSA GKTQLALQLC LAVQFPRQHG GLEAGAVYIC TEDAFPHKRL QQLMAQQPRL RTDVPGELLQ KLRFGSQIFI EHVADVDTLL ECVNKKVPVL LSRGMARLVV IDSVAAPFRC EFDSQASAPR ARHLQSLGAT LRELSSAFQS PVLCINQVTE AMEEQGAAHG PLGFWDERVS PALGITWANQ LLVRLLADRL REEEAALGCP ARTLRVLSAP HLPPSSCSYT ISAEGVRGTP GTQSH; Positive Samples: HL-60; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, perinuclear region
靶标信息
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RAD51 like; XRCC 3
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