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Proteintech
YPEL3 Polyclonal Antibody
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产品信息
15403-1-AP
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
YPEL3 Fusion Protein Ag7626 (1-119 aa encoded by BC005009)
偶联物
形式
Liquid
浓度
0.3 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
15403-1-AP was raised against full length of YPEL3 protein (1-119 aa); it can recognize YPEL1-4.
Immunogen sequence: MVRISKPKT FQAYLDDCHR RYSCAHCRAH LANHDDLISK SFQGSQGRAY LFNSVVNVGC GPAEERVLLT GLHAVADIHC ENCKTTLGWK YEQAFESSQK YKEGKYIIEL NHMIKDNGWD (1-119 aa encoded by BC005009)
靶标信息
YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
