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The envelope (E) protein of the Yellow Fever Virus (YFV) is a critical component of the virus's structure and function, playing a pivotal role in the virus's ability to infect host cells. This glycoprotein is located on the surface of the virion and is responsible for mediating the attachment of the virus to host cell receptors, facilitating viral entry through membrane fusion. The E protein is also involved in the induction of the host immune response, making it a primary target for neutralizing antibodies. Due to its essential functions in viral entry and immune recognition, the YFV E protein is a key target for vaccine development and antiviral therapies. Understanding the structure and function of the E protein has been instrumental in the design of live attenuated vaccines, such as the widely used 17D vaccine, which provides effective immunity against yellow fever. Ongoing research aims to further elucidate the mechanisms of E protein-mediated viral entry and immune evasion, with the goal of improving existing vaccines and developing novel therapeutic strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。