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Proteintech
ZBTB1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
26287-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZBTB1 Fusion Protein Ag23492 (1-357 aa encoded by BC050719)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.17 mg/mL
规格
25.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAKPSHSSY VLQQLNNQRE WGFLCDCCIA IDDIYFQAHK AVLAACSSYF RMFFMNHQHS TAQLNLSNMK ISAECFDLIL QFMYLGKIMT APSSFEQFKV AMNYLQLYNV PDCLEDIQDA DCSSSKCSSS ASSKQNSKMI FGVRMYEDTV ARNGNEANRW CAEPSSTVNT PHNREADEES LQLGNFPEPL FDVCKKSSVS KLSTPKERVS RRFGRSFTCD SCGFGFSCEK LLDEHVLTCT NRHLYQNTRS YHRIVDIRDG KDSNIKAEFG EKDSSKTFSA QTDKYRGDTS QAADDSASTT GSRKSSTVES EIASEEKSRA AERKRIIIKM EPEDTPTDEL KDFNIIKVTD KDCNESTD (1-357 aa encoded by BC050719)
靶标信息
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
protein homodimerization activity
protein heterodimerization activity
K63-linked polyubiquitin binding
negative regulation of transcription from RNA polymerase II promoter
regulation of cytokine production
regulation of immune system process
positive regulation of T cell mediated immunity
DNA repair
chromatin remodeling
cellular response to DNA damage stimulus
translesion synthesis
positive regulation of natural killer cell differentiation
cellular response to UV
mRNA transcription from RNA polymerase II promoter
positive regulation of T cell differentiation
thymus development
protein homooligomerization
positive regulation of pro-T cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
