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Invitrogen
ZC3H12A Polyclonal Antibody
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ZC3H12A Antibody (PA5-115556) in IHC (P)
Immunohistochemistry analysis of ZC3H12A in human kidney cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115556) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115556
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ZC3H12A(Accession Q5D1E8), corresponding to amino acid residues V222-D272.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MCPIP1.
靶标信息
ZC3H12A is an MCP1 -induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endoribonuclease ZC3H12A; MCP-1 treatment-induced protein; MCP-induced protein 1; Monocyte chemotactic protein-induced protein 1; Reg1; Regnase-1; ribonuclease ZC3H12A; RP3-423B22.1; zc3h12a; zc3h12a {ECO:0000312|RGD:1306776}; Zinc finger CCCH domain-containing protein 12A
基因别名: BC036563; MCPIP; MCPIP1; RGD1306776; ZC3H12A
UniProt ID: (Rat) A0JPN4, (Mouse) Q5D1E7
Entrez Gene ID: (Rat) 313587, (Mouse) 230738
angiogenesis
apoptotic process
positive regulation of autophagy
positive regulation of gene expression
negative regulation of gene expression
positive regulation of lipid storage
cell differentiation
negative regulation of NF-kappaB transcription factor activity
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of nitric oxide biosynthetic process
positive regulation of fat cell differentiation
cellular response to lipopolysaccharide
nucleic acid phosphodiester bond hydrolysis
positive regulation of reactive oxygen species metabolic process
multicellular organism development
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