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Rockland
ZCRB1 Polyclonal Antibody
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ZCRB1 Antibody (600-401-GC9) in WB
Western Blot of ZCRB1 antibody. Lane 1: Raji cell lysate with ZCRB1 antibody at 1 µg/mL. Lane 2: Raji cell lysate with ZCRB1 antibody at 2 µg/mL. Load: 35 µg per lane. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 25 kDa, 20 kDa for ZCRB1. Other band(s): ZCRB1 splice variants and isoforms.
产品信息
600-401-GC9
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-ZCRB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human ZCRB1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MADP-1; MGC26805; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; zinc finger CCHC-type and RNA binding motif 1; Zinc finger CCHC-type and RNA-binding motif-containing protein 1
基因别名: 2700088M22Rik; MADP-1; MADP1; RBM36; RGD1309851; SNRNP31; ZCCHC19; ZCRB1
UniProt ID: (Human) Q8TBF4, (Rat) Q499V6, (Mouse) Q9CZ96
Entrez Gene ID: (Human) 85437, (Rat) 362990, (Mouse) 67197
