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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RLRKRYPTNN FGNCTGCSAT FSVLKKRRSC SNCGNSFCSR CCSFKVPKSS MGATAPEAQR ETVFVCASCN QTLSK
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 97%.
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protrudin; RP11-459F3.2; Spastic paraplegia 33 protein; Zinc finger FYVE domain-containing protein 27
基因别名: SPG33; ZFYVE27
Entrez Gene ID: (Human) 118813