Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
ZNF496 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
20900-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZNF496 Fusion Protein Ag15015 (238-587 aa encoded by BC007263)
偶联物
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LDPAQTGFY GEFIIGEDYG VSMPPNDLAA QPDLSQGEEN EPRVPELQDL QGKEVPQVSY LDSPSLQPFQ VEERRKREEL QVPEFQACPQ TVVPQNTYPA GGNPRSLENS LDEEVTIEIV LSSSGDEDSQ HGPYCTEELG SPTEKQRSLP ASHRSSTEAG GEVQTSKKSY VCPNCGKIFR WRVNFIRHLR SRREQEKPHE CSVCGELFSD SEDLDGHLES HEAQKPYRCG ACGKSFRLNS HLLSHRRIHL QPDRLQPVEK REQAASEDAD KGPKEPLENG KAKLSFQCCE CGKAFQRHDH LARHRSHFHL KDKARPFQCR YCVKSFTQNY DLLRHERLHM KRRSKQALNS Y (238-587 aa encoded by BC007263)
靶标信息
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: MGC15548; NSD1 (nuclear receptor binding SET-domain containing 1)-interacting zinc finger protein 1; NSD1-interacting zinc finger protein 1; Zinc finger protein 496; Zinc finger protein with KRAB and SCAN domains 17
基因别名: NIZP1; Nizp11; ZFP496; ZKSCAN17; ZNF496; ZSCAN49
UniProt ID: (Human) Q96IT1, (Mouse) Q5SXI5
Entrez Gene ID: (Human) 84838, (Mouse) 268417
