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Sequence of this protein is as follows: MAQEPVTFRD VAIYFSREEW ACLEPSQRAL YRDVMLDNFS SVAALGFCSP RPDLVSRLEQ WEEPWVEDRE RPEFQAVQRG PRPGARKSAD PKRHCDHPAW AHKKTHVRRE RAREGSSFRK GFRLDTDDGQ LPRAAPERTD AKPTAFPCQV LTQRCGRRPG RRERRKQRAV ELSFICGTCG KALSCHSRLL AHQTVHTGTK AFECPECGQT FRWASNLQRH QKNHTREKPF CCEACGQAFS LKDRLAQHRK VHTEHRPYSC GDCGKAFKQK SNLLRHQLVH TGERPFYCAD CGKAFRTKEN LSHHQRVHSG EKPYTCAECG KSFRWPKGFS IHRRLHLTKR FYECGHCGKG FRHLGFFTRH QRTHRHGEV
The ZNF707 gene, a member of the zinc-finger protein (ZNF) family, encodes a transcription factor that can significantly influence various cellular processes by binding to DNA and regulating gene expression. Located on chromosome 4q32, zinc-finger proteins like ZNF707 are characterized by their zinc-finger motifs, which enable their interaction with specific DNA sequences. Mutations in ZNF707, such as rs4873815-TT, have been implicated in the tumorigenesis and prognosis of ovarian clear cell adenocarcinoma (Ov-CCA), highlighting its clinical significance in cancer research. Research also suggests that missense mutations in ZNF genes can alter protein-DNA interactions, potentially leading to cancer development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger protein 707
基因别名: ZNF707
UniProt ID: (Human) Q96C28
Entrez Gene ID: (Human) 286075