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Invitrogen
ZNHIT2 Polyclonal Antibody
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产品信息
PA5-63517
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CTPVVPTRIP AIVSLSRGPV SPLVRFQLPN VLFAYAHTLA LYHGGDDALL SDFCATLLGV SGALGAQQVF ASAEEAL
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
靶标信息
The ZNHIT2 gene, located on chromosome 7, encodes a zinc-finger HIT-type containing protein crucial for various cellular processes, such as chromatin remodeling and gene transcription regulation. Knockout studies in mice reveal that ZNHIT2, alongside ZNHIT1, is essential during early development, with deficits leading to embryonic lethality during peri-implantation stages due to reduced proportions of pluripotent inner cell mass cells and aberrant expression of key developmental genes like NANOG and SOX17. This gene's relevance extends to its involvement in protein-protein and protein-nucleic acid interactions that are fundamental in cellular functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein FON; Zinc finger HIT domain-containing protein 2; zinc finger, HIT domain containing 2; zinc finger, HIT type 2; zinc finger, HIT-type containing 2
基因别名: C11orf5; FON; ZNHIT2
UniProt ID: (Human) Q9UHR6
Entrez Gene ID: (Human) 741
