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Fabgennix
Zika Virus NS5 Polyclonal Antibody, FITC
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产品信息
ZIKANS5-FITC
产品规格
种属反应
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic pepitde taken within amino acid region 3230-3280 on Zika virus NS5 protein.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Zika Virus nonstructural protein 5 (NS5) interacts with the host retinoic acid-inducible gene I (RIG-I), which is an essential signaling molecule for defending pathogen infections. NS5 subsequently represses K63-linked polyubiquitination of RIG-I, attenuates the phosphorylation and nuclear translocation of interferon regulatory factor 3 (IRF3), and inhibits the expression and production of interferon-beta (IFN-beta), thus restricting the RIG-I signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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