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Alomone Labs, LTD
ZnT4 (SLC30A4) Polyclonal Antibody
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ZnT4 (SLC30A4) Antibody (AZT-014-200UL) in IHC (F)
Expression of ZnT4 in mouse hypothalamus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti-ZnT4 (SLC30A4) Antibody (#AZT-014) (1:200), followed by goat anti-rabbit-AlexaFluor-488. A. ZnT4 immunoreactivity (green) appears in neuron outlines (arrows). B. Pre-incubation of the antibody with ZnT4 (SLC30A4) Blocking Peptide (BLP-ZT014), suppressed staining. Cell nuclei are s... View More
产品信息
AZT-014-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide DEVSDEGLSRFNKLR, corresponding to amino acid residues 33-47 of rat SLC30A4. Intracellular, N-terminus.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: DEVSDEGLSRFNKLR
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dri 27 protein; Dri 27/ZnT4 protein; Lethal milk protein; Probable proton-coupled zinc antiporter SLC30A4; solute carrier family 30 (zinc transporter), member 4; solute carrier family 30 (zinc transporter), member 4; zinc transporter 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4
基因别名: Lm; SLC30A4; znT-4; ZNT4
UniProt ID: (Human) O14863, (Rat) O55174, (Mouse) O35149
Entrez Gene ID: (Human) 7782, (Rat) 64469, (Mouse) 22785
