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Nordic
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Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
The antiSerum does not cross-react with any other Human plasma proteins as tested in geldiffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to mammalian Serum proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail.
In immunoelectrophoresis use 2 µL serum or equivalent against 120 µL antiserum. In double radial immunodiffusion use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL amniotic fluid or hepatoma serum samples (neat and serially diluted) in 2 mm diameter peripheral wells.
Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at 4°C, not refrozen, and preferably used the same day.
ORM1 is an acute phase plasma protein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. ORM1 is a major acute phase reactant, both in human and in rat. In human plasma, ORM1 (44 kDa) is found at levels of 0.5-1.4 mg/mL. Its concentration in blood plasma is elevated during acute inflammation, such as trauma, malignancies, myocardial infarction, rheumatoid arthritis, bacterial infections, after major surgery, in cases of chronic pain etc, and can be used for the diagnosis of inflammatory conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AGP 1; Alpha-1-acid glycoprotein 1; epididymis secretory sperm binding protein Li 153w; OMD 1; Orosomucoid-1
基因别名: AGP-A; AGP1; HEL-S-153w; ORM; ORM1
UniProt ID: (Human) P02763
Entrez Gene ID: (Human) 5004