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PA1-32558 detects alpha 1b Adrenoceptor from human samples.
PA1-32558 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32558 immunogen is: Synthetic peptide, KLH conjugated.
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。